Immune deficiency problems can be temporary or permanent. Temporary immune deficiency can be caused due to the variety of sources that weakens the immune system.There are several causes that suppress the immune system which usually includes influenza and mononucleosis, autoimmune disorders, rheumatoid arthritis. Sometimes, these problems are assosiated during birth or early childhood.
What is human normal immunoglobulin? Human immunoglobulin consists of plasma which is made from 1000 donors. They provide antibodies that fight against foreign substances and provide resistance to infectious diseases. This injection is used to treat immunoglobulin disorders. They are used to treat primary immune deficiency as well as secondary immune deficiency. Immunoglobulins have an important role in the immune system as they identify the antigen that aids in destruction. They also reduce inflammation, and immunity is increased.
Did you know about different types of immunological disorders? There are two types of immunological disorders: primary and secondary immunodeficiency disorders. Primary immunodeficiency disorder is usually present from birth and diagnosed during infancy or early childhood and is inherited. They are usually caused due to genetic mutations in a different part of the immune system. It tends to cause chronic susceptibility to infection.x- linked combined immunodeficiency causes mutations in the signaling receptor genes thereby causing T-cells and natural killer cells inactive causing immunological disorders..
Secondary immunodeficiency disorders usually occur in the later stage of life due to certain medications and long-term disorders such as HIV and diabetes.when immune cells become the ultimate target then the individuals are immunosuppressed. Incase of HIV, they usually target T cells, and secondary infection occurs due the alterations in the immune system.Patients undergoing chemotherapy, bone marrow transplants, organ transplants, immunosuppressive drugs weaken the immune system. pregnancy is another reason where the immune system is suppressed leading to microbial infection.
Autoimmune disorders: These autoimmune disorders which play a major role in the immune suppression. In case of type 1 diabetes mellitus, the immune cell identifies its own insulin producing beta cells as a foriegn substance and tries to destroy it. This case is known as autoimmune disorder.Some of the autoimmune diseases where the immune system gets suppressed are systemic lupus erythematosus, sickle cell anemia,rheumatoid arthritis,multiple sclerosis.
There are several diagnostic tests to confirm immunodeficiency diseases, the most common among them is blood test and prenatal test.Blood test usually determines the amount of immunoglobulins in the blood and measures the levels of blood cells, immune system cells that indicates the immune system defect. A prenatal test should be done in women who already have children with primary immunodeficiency disorders. There are several treatments available to reinstitute the immune system. One among them is stem cell transplantation where normal stem cells are transplanted to the person with immunodeficiency. Gene therapy is the procedure which is done in primary immunodeficiency,where the stem cells are corrected and returned back to the person through intravenous fusion. In gene therapy, there is no need for donor, patients own cells are used.
Bharglob 16.5% acts as an immunizing agent and supports the immune system by producing the required antibodies to fight against foreign bodies and infectious diseases. They enhance the immune system's functions and reduce the risk factors of autoimmune disorders.Some common side effects include headache, sometimes there will be swelling, or skin becomes hard at the site of injection. Patients feel pain in the face, back, arms, legs, joints, or neck, fever, running nose, sore throat, dry mouth, blisters in mouth and throat, and tightness.
There will be a sudden fall of blood pressure in the patients with shock and allergy so please monitor for 20 minutes after the infusion of this bharglob 16.5% injection. If there is any severe headache, drowsiness, nausea, vomiting, and stiffness, inform your doctor immediately. This medication should be used with caution in patients with diabetes, overweight, high blood pressure, and blood clotting disorders as they develop a higher risk of the blood clot. It should be used with caution in kidney patients and heart-related disorders. Inform your doctor of any shortness of breath or difficulty in breathing.