Severe Aplastic Anaemia (SAA) is a serious blood disease that occurs when the bone marrow fails to produce enough new blood cells. It is called "aplastic" because the bone marrow stops producing the stem cells that form blood cells, and it is considered "severe" because of the significant impact it has on the body's ability to produce enough blood cells.
Etiology:-
Exposure to certain chemicals or drugs
Genetic factors
Symptoms:-
Fatigue
Muscle weakness
Shortness of breath
Pale skin
Nose bleeds
Petechiae (small red or purple spots on the skin)
Diagnosis:-
CBC Tests- It is a common blood test that provides information about the number and type of blood cells in the body.
D-Dimer Test- It is a blood test that measures the level of a protein fragment called D-dimer. This test is used to help diagnose blood clots or thrombus formation in the body.
Bone marrow Biopsy- This can be performed using a special needle that is inserted into the bone marrow space, usually in the hip bone. A small sample of bone marrow tissue is taken out for examination.
Genetic Testing- The test can be done using a variety of samples, including blood, saliva, or tissue samples. The purpose of the testing is to identify inherited genetic disorders.
Treatment:-
Blood Transfusions: To replace the missing blood cells.
Immunosuppressive Therapy: This therapy is carried out to suppress the immune system and allow the bone marrow to recover.
Bone Marrow Transplant: It restores the damaged bone marrow with healthy stem cells.
Prevention:-
You can lower your chances of getting this disorder by avoiding medications that thin the blood and raise your chances of bleeding.
Avoid coming into contact with chemicals like benzene, arsenic, and pesticides can be helpful in preventing the condition.
Exercise caution is required when engaging in sports or other activities that may cause bruising or bleeding.
Take extra precautions when shaving, brushing your teeth, and blowing your nose.
Get vaccinated for viruses that can harm your platelets.
If you have a family history of SAA, it may be advised to get regular blood tests to monitor for any abnormalities. Early detection and treatment can help prevent the condition from worsening.
Revolade 25mg Tablet is a medication used to treat low blood counts caused by severe aplastic anaemia (SAA). The active ingredient in Revolade is Eltrombopag, which works by stimulating the bone marrow to produce more platelets, red blood cells, and white blood cells. This tablet helps to improve these symptoms by increasing the production of blood cells in the bone marrow. The common side effects include nausea, common cold, hair loss, joint pain, headache and loss of appetite. If you have severe aplastic anaemia, then Revolade 25mg Tablet might be prescribed to you by your doctor to treat this disorder.